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In clinical trials including MAESTRO-NASH, Resmetirom reduced hepatic fat content (as measured by MRI-PDFF), lowered liver enzyme values, improved noninvasive markers of liver fibrogenesis, and decreased liver stiffness [125,126]

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Numerical laboratory data, such as systolic and diastolic blood pressure, body mass index (BMI), and glycated hemoglobin (HbA1c), were included as critical cardiovascular and metabolic health markers