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Description
Use of a GLP-1 drug for one to three years was associated with a higher risk of thyroid cancer overall (hazard ratio about 16) and of medullary thyroid cancer specifically (about 18)

This trial led the FDA to expand Wegovy's label to include reducing cardiovascular risk in people with obesity

Thus, GLP-1RA mediates inflammation to prevent formation of neurotoxic astrocytes which cause RGC death

Novo Nordisk advanced amycretin, a GLP-1/amylin receptor agonist, straight to Phase 3 after early results showed weight reductions up to 24.3%

Russo, A
