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39 Anaesthetic guidelines are available for reference (see: Muscle loss Weight loss occurring with the use of GLP-1 receptor agonists, GLP-1/GIP dual receptor agonists and bariatric surgery is invariably associated with some muscle loss, and thus potentially leading to unintended outcomes such as loss of strength or increased likelihood of falls

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For people whose health doesnt depend on body weight reductions, the potential side effects may be difficult to justify