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Research shows that prebiotics can help increase GLP-1 secretion

Methods Adults (18 years old) with T2D required at least one prescription for injectable semaglutide at index date (treatment switch), at least one prescription for any other GLP-1 RA in the previous 365 days, a baseline HbA1c and/or weight measurement in the 90 days pre-index and a follow-up measurement at 180 and 365 days post-index

Meanwhile, orforglipron demonstrated significant weight loss efficacy [8] consistent with injectable GLP-1 medicines

Advanced 15-in-1 GLP-1 Support for Weight Management: KetoZest GLP-1 Support combines a powerful 15-in-1 blend of Liposomal Berberine, Ceylon Cinnamon, Green Tea Extract, and other selected botanicals and nutrients for natural GLP-1 Support, which plays a key role in regulating appetite and energy levels

: GI distress occurs in 1 out of 3 patients (often temporary)