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Characterization and implications of the initial estimated glomerular filtration rate dip upon sodium-glucose cotransporter-2 inhibition with empagliflozin in the EMPA-REG OUTCOME trial

The major clinical guidelines from the PROT-AGE Study Group and the European Society for Clinical Nutrition and Metabolism (ESPEN) recommend 1.01.2 grams of protein per kilogram of body weight per day, for healthy older adults, with **1.21.6 g/kg** for those exercising regularly or managing significant weight loss or chronic illness. A woman on a GLP-1 who is also doing resistance training falls squarely in the higher range