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Ruhoy emphasized the potential for GLP-1 medications to stabilize mast cells, reduce inflammation, and improve energy production

FDA Label Garvey WT, Frias JP, Jastreboff AM, et al

Obesogenic Neighborhood Environments, Child and Parent Obesity: The Neighborhood Impact on Kids Study
However, it has also been reported that although deletion of hepatocyte Dpp4 expression abolished the obesity-induced rise in circulating DPP-4 and was associated with reduced levels of proinflammatory cytokines in hepatocytes and adipose tissue, levels of circulating soluble DPP-4 per se did not correlate with tissue or systemic inflammation (82)

However, like other drugs in its class, tirzepatide shares a similar safety profile, with specific side effects that patients should be aware of