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McGuire, found that oral semaglutide reduced major adverse cardiovascular events (MACE) to 3.1 events per 100 person-years, compared to 3.7 events in the placebo group a 14% reduction (HR 0.86) over a median follow-up of 49.5 months

Another exciting finding is that leptin reduction may be an alternative strategy toward reversing liver fibrosis, independent of weight loss

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[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Yamane S, Harada N, Inagaki N (2016) Mechanisms of fat-induced gastric inhibitory polypeptide/glucose-dependent insulinotropic polypeptide secretion from K cells

Moreover, they found their menstrual cycle was better regulated after struggling with PCOS