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Administration of GLP-1 and exendin-4 promoted neurite outgrowth in cultured dorsal root ganglion (DRG) neurons, presumably explaining the increased nerve fibers observed in biopsies of IBS individuals [51]

Alginate-based products (such as Gaviscon) may also be helpful for reflux symptoms as they form a protective layer on top of stomach contents

Ice Pack (Optional): Briefly cooling the skin before injection can numb the area

Based on insurance claims data from Purple Lab, a Pennsylvania health analytics company, a 2024 report published by GLP-1 Newsroom broke down the estimated number of weight-loss and diabetes drug prescriptions per state

Subjects typically increased from 2 mg to 4 mg, then to 8 mg, and in some arms up to 12 mg once weekly, following fixed timetables set by the research protocol