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see also review by Brierley & de Lartigue, 2021), or even elsewhere close to the circulation, which in turn release glutamate and peptide cotransmitters within the lower brainstem to convey postprandial satiation signals to the CNS (Figure 1)

Fabbrini E, Tamboli RA, Magkos F, Marks-Shulman PA, Eckhauser AW, Richards WO, et al

High out-of-pocket costs, complex cost-sharing structures, and gaps in prescription drug coverage are major healthcare policy barriers to medication use in underserved and older patient populations

While these actions are similar to those of GLP-1 analogs like Wegovy and Zepbound, there is some evidence that, compared to GLP-1 drugs, amylin analogs are better tolerated and help preserve lean muscle mass

After all, in the biomedical field, safety is the ultimate indicator that determines the product life cycle