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Weeks 17 through 20: escalation to 12.5mg Few people need 12.5mg

[DOI] [PubMed] [Google Scholar] 88.Kawai T, et al

Some other treatments for Type 2 diabetes can actually cause weight gain, whereas GLP-1RA drugs effectively control blood glucose levels while also reducing body weight, Yuan said

Adverse Events In both phase 2 trials, there were no major safety signals with retatrutide use [45, 46]

They can also be used safely at low eGFR, and initiation or continuation in dialysis patients is associated with lower cardiovascular risk and mortality