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These bacteria colonize your gut and begin producing postbiotic metabolites, primarily butyrate, propionate, and a protein called P9

Although the weight loss mechanism is not well-understood, GLP-1RAs curb hunger, leading to a reduction in food intake
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When GIPRAs and GLP-1RAs were co-administered to obese mice, the combination significantly enhanced both appetite suppression and weight loss compared to monotherapy [33, 34]
Tirzepatide, a dual GLP-1/GIP receptor agonist, produces even greater reductions in glucose and body weight in preclinical trials
