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doi: 10.1210/en.2003-0007
Increased expression and release of proinflammatory cytokines (TNF-, IL-1, and IL-6) have been described both in vitro and in vivo [156]

In addition, GLP-1RA therapy has been associated with favorable shifts in gut microbiota composition, including enrichment of short-chain fatty acid-producing bacteria, which promote Treg activity and suppress pro-inflammatory Th17 responses [43,44]

Wegovy-related symptoms often emerge or worsen within a few days of starting the medication or increasing the dose, and they may improve as the body adjusts

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