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Clinical Trials Assessing the Efficacy of Semaglutide in Lupus To date, limited clinical data are available on the use of Semaglutide in lupus patients, as its primary indication remains focused on diabetes management

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Medications studied included: GLP-1 receptor agonists (e.g., semaglutide) Dual GLP/GIP agonists (e.g., tirzepatide) Other AOMs like orlistat and phentermine-topiramate After discontinuation, most participants saw measurable weight regain by the 8-, 12-, and 20-week marks