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While missing this deadline does not create immediate legal consequences, ignoring the letter signals non-compliance, making litigation more likely

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A licensed provider determines clinical appropriateness

Blood sugar regulation gets trickier

Preliminary data point toward beneficial effects of GIP agonism, as reported in findings from the SURPASS program that tirzepatide reduced UACR and slowed down eGFR declined in comparison with both placebo (53) and comparator drugs including insulin glargine (74, 75)