glp 1 agonists long term effects Long-term Success of GLP-1s Hinges on More Than Just a Prescription The expanding role of GLP-1

Author Contributions Stephano Cedirian, Michela Starace, Emanuel Raschi, Francesca Pampaloni, Monia Donati, Rossella Sgarzani, Luca Negosanti, Luca Rapparini and Michelangelo La Placa conceptualized and designed the study, conducted data collection and analysis, and wrote the initial draft of the manuscript

Heres where it gets interesting: both GLP-1s and psychedelics act on the brains reward centers (ventral tegmental area and nucleus accumbens)

Edvardsson CE, Adermark L, Gottlieb S, Alfreji S, Emous TA, Gouda Y, Thorsell A, Vujii M, Arans C, Benrick A, Wernstedt Asterholm I, Lopez MF, Becker HC, Jerlhag E

The final sample ( N = 20) consisted of majority white females, with a mean age of ~ 36 years and mean BMI of ~ 38

Additionally, Semaglutide is not recommended for individuals with a history of pancreatitis, as there is a slight risk of pancreatic inflammation associated with GLP-1 receptor agonists