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Even short 1020 min sessions have significant metabolic benefits: Increases post-exercise fat burn (EPOC) Improves insulin sensitivity Mobilises abdominal fat Enhances mitochondrial function in muscle How to Get Started With HIIT Beginner options: 30 sec fast walk / 60 sec normal pace 6 rounds Stationary bike: 15 sec sprint / 45 sec easy 8 rounds Circuit: squats, climbers, jumping jacks, lunges (30 sec on / 30 sec rest) Aim for 24 sessions per week

Metabolic rate drops by 200 to 500 calories daily beyond what reduced body mass would predict

However, it is reasonable to assume that the increased risk of nausea and vomiting during anesthesia increases the risk of aspiration in patients taking these drugs

Discontinuation typically results in weight regain, with patients recovering approximately two-thirds of lost weight within 12 months after stopping treatment

The same hormonal signaling that suppresses appetite and drives weight loss also accelerates colonic transit and increases water secretion in the lower bowel, especially during the first few weeks of treatment and after each dose increase