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Some observational data suggest that weight loss achieved through any meansincluding GLP-1 medications, bariatric surgery, or lifestyle modificationmay have modest effects on thyroid function tests in individuals with obesity

RF-409 was cloned with a N-terminal His6x tag with a TEV cleavage site and C-terminal FLAG tag in a pet29 based vector

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By stimulating insulin production, GLP-1 helps lower blood sugar levels post-meal, ensuring better glucose control

However, these medicines differ in their mechanisms and current approval status