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Its also important to consider your current medications

A buffer layer (towel or foam) between the ice pack and the vial is essential

Consistent refrigerator storage beats accidentally frozen storage for most applications

Acceptable timing adjustments include: Missed dose recovery : If a missed dose is remembered within four days (96 hours) of the scheduled injection time, patients should administer the dose as soon as possible and then resume the regular weekly schedule

In SURMOUNT-1 (NEJM 2022, 2,539 adults with obesity), the 15 mg arm averaged 22.5% body weight loss at 72 weeks, the 10 mg arm 21.4%, and the 5 mg arm 16.0%