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The most common ones reported in clinical trials include: Nausea Upset stomach Mild headaches These side effects are usually temporary and tend to improve over time

For example, the SELECT trial reported that semaglutide reduced the risk of MACE by 20% (Hazard Ratio (HR) 0.80, 95% confidence interval (CI) 0.720.90) in people with obesity but without diabetes, although several secondary outcomes did not reach statistical significance under hierarchical testing procedures

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If you're wondering how tirzepatide works, each injection integrates seamlessly with your body's natural systems, targeting appetite regulation and improving sugar metabolism