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If cost is a central factor, the Medicare program may have a big impact

Switching to once-daily liraglutide from twice-daily exenatide further improves glycemic control in patients with type 2 diabetes using oral agents
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Remarkably, despite the theoretical potential of enhancing L cell secretion for the treatment of metabolic disorders (1), there has been scant progress in clinical development of GLP-1 secretagogues exhibiting sustained efficacy in both preclinical and clinical studies
