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Fitch Ratings forecasts in a report published last week that overall revenue from the Strip will be down by 60% in 2020, and down by 50% in 2021

The company has not publicly confirmed a submission date, but its quarterly investor calls have consistently described retatrutide as a "late-stage pipeline priority." Lilly could also pursue a pre-NDA meeting with the FDA, where the agency provides informal guidance on what the application should contain

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Participants in Retatrutide trials described their experience not simply as reduced appetite but as genuine disinterest in food

Preclinical and clinical studies suggest that GLP-1RAs may reduce EAT volume/thickness, potentially exceeding overall weight loss, attenuate EAT inflammation and fibrosis, improve cardiomyocyte calcium handling, mitigate oxidative stress, and suppress pulmonary vein ectopy, thereby potentially reducing AF susceptibility and recurrence post-ablation