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Those numbers made retatrutide the most potent weight loss peptide ever studied in clinical trials
doi: 10.1161/CIRCULATIONAHA.121.053766 [DOI] [PubMed] [Google Scholar] 95.Sarafidis P, Ferro CJ, Morales E, et al

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In addition to its ability to stimulate GH secretion and gastric motility, ghrelin stimulates appetite and induces a positive energy balance that leads to weight gain