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Description
As of early 2026, several potent single, dual, and triple incretin receptor agonists are in Phase 2/3 trials for MASH including : Survodutide : A dual glucagon (GCGR)/GLP-1 receptor agonist that has shown significant MASH resolution in Phase 2 trials
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Simultaneously, GLP-1 interacts with afferent vagal fibers that transmit the signal to the brainstem and the hypothalamus
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