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Daily preventive laxatives are unnecessary if hydration, fiber, and activity manage your constipation adequately

Additionally, an NSAID can lessen the effect of hydrochlorothiazide because NSAIDs can increase blood pressure

Endocrine journal, 66(1), 51-63 Koo, H

It is approved in different strengths and dosing regimens and sometimes used in conjunction with other medications for a variety of conditions, including endometriosis, uterine fibroids, prostate cancer, precocious puberty in young children, and also is used off-label in gender-transitioning adolescents as hormone blockers, often in conjunction with gender-affirming hormones

Schmidt PT, Hartmann B, Bregenholt S et al (2000) Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells