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Description
Individual response varies significantly based on baseline gut microbiome composition, diet quality, and genetic factors

When the effects of age on renal function are taken into account, age alone did not have a clinically meaningful impact on the pharmacokinetics of sitagliptin based on a population pharmacokinetic analysis

Its generally considered effective, safe, inexpensive, and widely available

The real opportunity with microdosing is whether we can address metabolic dysfunction earlier, potentially before it becomes clinically problematic. Milder Side Effects Microdosing may enable a much gentler onboarding process

"Dieting & Gallstones." National Institutes of Health
