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can you take semaglutide with gallstones Cause Gallbladder Issues? Risks and Symptoms Mounjaro, Wegovy & Gallstones: Surgical
Description
A landmark randomized clinical trial published in JAMA Psychiatry in April 2025 evaluated weekly semaglutide in adults with alcohol use disorder

In the same head-to-head trial, those on the maximum semaglutide dose achieved an average loss of 13.7%

So there are benefits, for sure

Because the insulinotropic action of GLP-1 is dependent on the presence of hyperglycemia, long duration activity does not increase the risk of hypoglycemia
Patients who stay on treatment through six months nearly double their weight loss, and maximum benefits appear around the one-year mark