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Furthermore, systemic MOTS-c treatment protected pancreatic islets from T cell-mediated infiltration in autoimmune NOD mice 7,10 and STZ-induced -cell apoptosis in gestational diabetic C57BL/6J mice 87

Added sugars are those added during food processing (CDC 2024)

LEAP2 concentrations also seem sensitive to intestinal exposure to specific substrates, such as glucose, lactate, -hydroxybutyrate, and oleic acid, underscoring the need for further studies on the link between nutrient sensing and LEAP2 regulation [60, 61]

Miglioramenti nel BMI e nelle Misure Antropometriche * Riduzione del BMI: Una maggiore proporzione di pazienti trattati con semaglutide ha raggiunto un miglioramento nella categoria del BMI, arrivando a un BMI sano e superando il punto di cutoff della circonferenza vita, oltre il quale aumenta il rischio cardiometabolico specifico per sesso e razza

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