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GLP-1 medications interact with certain drugs, supplements, and substances that may reduce efficacy or increase side effects

And at what point should we all be on it?

In a trial, people lost 75% fat and 25% muscle.

About one in eight adults (12%) say that they are currently taking a GLP-1 drug such as Ozempic or Wegovy either to lose weight or treat a chronic condition, an increase from 18 months ago, though the high costs of the medications remain a concern, a new KFF Health Tracking Poll finds.

Importantly, increasing the endogenous production of GLP-1 by different mechanisms or by increasing the number of intestinal L-cells that tend to produce this hormone may be another effective therapeutic approach to managing T2DM