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He is on a data monitoring and safety board for Inventiva

A recent meta-analysis of six studies involving 2071 participants found that GLP-1 RA treatment significantly reduced depression rating scale scores compared to control treatments (standardized mean difference, 0.12

- Drugs.com, accessed April 22, 2025, Don't Worry About Muscle Loss With GLP-1 Inhibitors, Viewpoint Asserts | tctmd.com, accessed April 22, 2025, Coping With Common Side Effects of GLP-1 Medications - Lose It!, accessed April 22, 2025, Why All Ozempic, Wegovy Patients Should Consider a Plant-Based Diet - Forks Over Knives, accessed April 22, 2025, GLP-1 Agonists: What They Are, How They Work & Side Effects - Cleveland Clinic, accessed April 22, 2025, GLP-1 Weight-Loss Program | WeightWatchers, accessed April 22, 2025, Wegovy, Zepbound: 4 Ways to Increase Weight Loss on GLP-1 Drugs, accessed April 22, 2025, 'Ozempic Diet': Foods to Eat and Avoid on a GLP-1 Obesity Drug - WebMD, accessed April 22, 2025, Exercise & Diet Strategies for Compounded GLP-1 Medications - Skippack Pharmacy, accessed April 22, 2025, New Year, New You: Kickstart Your Weight Loss Journey with GLP-1 Medications and Dietary Changes - MediThrive Personalized Wellness, accessed April 22, 2025, GLP-1 and Your Diet: Tips for Maximizing Weight Loss - LifeRx.md, accessed April 22, 2025, Your friendly guide to GLP-1 weight loss: what works, what doesn't and what's next, accessed April 22, 2025, GLP-1 Weight Loss Program: 4 Steps to Maximize Results Safely, accessed April 22, 2025, What Is It Like Losing Weight on a GLP-1

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Common side effects include: Gastrointestinal issues: Nausea, vomiting, constipation, and abdominal pain Injection site reactions: Redness, swelling, and pain Systemic issues: Fatigue, indigestion, heartburn, belching, and hair loss More severe side effects include: Thyroid problems: Medullary thyroid cancer and pancreatitis with severe, persistent abdominal pain Gallbladder problems with symptoms such as upper abdominal pain, fever, jaundice, or clay-colored stools Increased risk of hypoglycemia with symptoms such as dizziness, sweating, confusion, and shakiness Severe vomiting that leads to dehydration and kidney problems Mental health concerns such as depression and suicidal thoughts Vision changes from rapid changes in blood glucose levels Some patients should not use Zepbound, such as those who have or are at risk for medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2