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Description
This gradual approach helps reduce gastrointestinal discomfort

This step is personal and important, therefore it should feel clear and respectful

Semaglutide is a 31-amino acid peptide analog of human glucagon-like peptide-1 (GLP-1)

Tricyclic antidepressants have largely fallen out of favor for the treatment of depression, but bupropion remains commonly used

NICE recommends continuing metformin when adding a GLP-1 receptor agonist like semaglutide, as the combination addresses multiple aspects of metabolic dysfunction without significantly increasing hypoglycaemia risk when used alone
