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Is Semaglutide safe for long-term use

Amgens Phase 2 trial of MariTide showed remarkable efficacy: non-diabetic patients lost ~20% of body weight in 52 weeks (vs just 2.6% for placebo)

Dehydration from Ozempic-induced diarrhea may also increase the risk of blood clots, though a vitamin B-12 deficiency may also be to blame

Despite the generally high level of aggressiveness, there is considerable variability in the clinical outcome

The proposed explanation involves hormonal changes linked to GLP-1 medication use
