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Of those, the majority received treatment intensification ( n = 362

Specific alleles in FTO and MC4R may indicate baseline metabolic rate and appetite-regulation capacity

For example, the Krispy Kreme stock was downgraded by several investment banks from buy to hold, with the stock price dropping c.14% in the immediate wake of the SELECT trial announcement in August 2023 (from $14.40 to $12.43) due to the uncertain impact that the rise in weight-loss drugs will have on the future sales of the business