glp 1 mechanism of action weight loss Glucagon-like peptide-1 receptor: mechanisms and advances in therapy GLP-1 and health: Beyond weight

Fortunately, advanced weight loss treatments now not only help shed pounds but also enhance metabolic and heart health

Kidney Int 105(4S):S117S314 Perkovic V, Tuttle KR, Rossing P, FLOW Trial Committees and Investigators et al (2024) Effects of semaglutide on chronic kidney disease in patients with type 2 diabetes

In this study, participants using semaglutide had a lower risk for CVD-related events when compared with placebo.38 These results build on prior evidence that GLP-1s not only support blood sugar and weight management but also offer significant cardiovascular protection in high-risk populations.39 A 2021 systematic review published in Diabetes & Metabolic Syndrome: Clinical Research & Reviews examined six studies involving over 182,000 adults with T2DM to evaluate the cardioprotective effects of GLP-1s (primarily liraglutide and exenatide) taken in conjunction with blood pressure and cholesterol lowering medications.40 The findings showed consistent improvements in cardiac function, including increased left ventricular ejection fraction40 and reduced heart chamber volume, along with weight loss and improved myocardial blood flow

Mojsov acknowledged the support from Diabetes Action in her Distinguished Medical Science Award acceptance speech and noted that the small grant helped supplement her NIH funding and allowed her to expand her research on GLP-1

On the whole, my symptoms have definitely been reduced since I stopped the mounjaro