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Most people regain 510% of weight lost within the first 3 months after stopping, then stabilize if lifestyle habits remain consistent

The most common side effects include nausea, upset stomach, constipation, fatigue, and headaches, which typically resolve with time

Same Active Ingredient, Same Safety Profile Although the starting dose is lower, the boxed warning, contraindications, warnings, and side effect profile are identical to standard semaglutide

Koshi Hashimoto is Vice-president, Japan Endocrine Society

It reflects a pharmacokinetic and pharmacodynamic balance between maintaining therapeutic drug levels and allowing the receptor cycling that preserves long-term effectiveness