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Improved Metabolic Health: The multi-receptor approach may enhance various aspects of metabolic health beyond just weight loss and glycemic control

Context dependence, receptor isoforms, and off-target considerations SLU-PP-332 is a pan-ERR agonist with the strongest potency at ERR

Currently, only injectable or oral prescription medications can deliver proven GLP-1 effects for weight loss

In an early study, treatment of adult rat cardiac myocytes with GLP-1 increased cAMP levels, but did not lead to increased cardiomyocyte contractility, as would be anticipated in the heart (Vila Petroff et al., 2001)

[DOI] [PubMed] [Google Scholar] 200.Nagasawa T., et al