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Women carrying certain variants may experience more pronounced weight regain during pregnancy or faster weight loss postpartum, patterns that affect treatment planning across the reproductive lifecycle

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FAQ Preliminary Phase 2 data shows Retatrutide achieved -24.2% weight loss in 48 weeks, while Mounjaro in Phase 3 showed -22.5% in 72 weeks

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4b), including Cyp8b1 which belongs to the primary BA synthetic pathway

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