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Cleve Clin J Med

Weight gain is also associated with greater Dpp4 expression in the liver of mice prone to diet-induced obesity, independently of the degree of intra-hepatic fat accumulation (87)

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It is responsible for up to 97% of glucose renal reabsorption and for about 5% of total renal Na + reabsorption

466 One study proposed a novel mechanism wherein postprandial GLP-1 release, under normal physiological conditions, inhibits the activity of chemosensory cells in the carotid body, thereby counteracting sympathetic excitability mediated by elevated blood glucose or insulin levels