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This finding underscores why maintenance dosing matters and why microdosing might serve as a viable long-term strategy for people who have achieved their weight loss goals but want to prevent regain without the side effects and costs of high-dose therapy

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4.3 Weight change 4.3.1 Uncontrolled studies While insulin monotherapy causes consistent weight gain, adding GLP-1RA leads to consistent weight loss

By 2025, GLP-1RAs are anticipated to receive FDA approval for new indications, such as chronic kidney disease, heart failure with preserved ejection fraction, and metabolic dysfunctionassociated steatohepatitis

Patients pay a flat monthly rate for their chosen medication tierwhether that is the Microdose Protocol at $129/month, compounded semaglutide at $149/month, or compounded tirzepatide at $249/month