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Gruessner AC, Sutherland DER, Gruessner RWG (2012) Long-term outcome after pancreas transplantation

Many times, diabetes requires more than one agent for treatment, but you must monitor for hypoglycemia when combining or adding new medications

A glucagon-bound full-length GCGR model (Siu et al., 2013) and models of agonist-docked full-length GLP-1R (Dods and Donnelly, 2015

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Ultimately, a Cu(I)-catalyzed coupling-cyclization enabled the formation of the tricyclic structure of the potent DPP-4 inhibitor 44 (Figure 6) (116)