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Excess adiposity is a particular overarching challenge in the treatment of type 2 diabetes because weight control can benefit so many of the other unmet needs by reducing metabolic stress to beta cells, improving insulin sensitivity and independently reducing the risk of associated morbidities [6]

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Patients using Semaglutide GLP-1 often experience greater weight loss compared to those on placebo, with some studies reporting up to 15% reduction in body weight

Tirzepatide, a dual GLP-1 and GIP receptor agonist, slows stomach emptying to regulate appetite and blood sugara mechanism that may cause heartburn or reflux in roughly 10-15% of early users

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