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Similarly, the thermogenic effect of glucagon receptor activation can feel unusual
GLP-1 is additionally believed to induce satiety via a direct effect within the central nervous system

11 In islet alpha-cells, prohormone convertase 2 modifies proglucagon to produce glucagon, which is formed by the removal of aa residues adjacent to 33 and 61 of proglucagon
Other companies are exploring different combinations of hormone agonists, different dosing strategies, and oral formulations of dual agonists
