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However, some patients anecdotally report these symptoms, which may relate to weight loss, metabolic changes, or other factors rather than a direct drug effect

11 Diabetes, Obesity and Metabolism GI tolerability of incretin therapiesReview of gastrointestinal side effects (nausea, GI discomfort) of GLP-1-based therapies and titration strategies

These medications effectively slow gastric emptying, which has raised concerns regarding the risk of residual gastric volume (RGV) and potential pulmonary aspiration during procedures requiring sedation

Daniel Rosen suggested that Ozempic poo might be caused by your bodys alert system: When you eat a large meal, there's something called the gastrocolic reflex, where the stretch in the top of the stomach alerts the very end of the colon and rectum to empty." He went on to say that GLP-1 medications like Ozempic and Wegovy can "trick your brain into thinking that food has arrived to the end of the intestines." Speaking to LADBible Group, Novo Nordisk shared the following statement: "Gastrointestinal (GI) events are well-known side effects of the GLP-1RA class