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Clinical data show that GLP-1 users usually regain weight without continued use, though people who lose more at first keep more off long-term (ending 12% lighter)

Your provider discusses potential considerations during your evaluation and provides guidance and follow-up if adjustments are needed

This article was first published Oct

Since people choosing to de-escalate their GLP-1 therapy might also be more motivated to adopt behavioral strategies for improving their health, there might be underlying selection bias in the study population

Combining both remains an off-label approach based on mechanistic theory rather than robust trial data