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A 2024 meta-analysis (Sattar et al., Lancet Diabetes Endocrinol) found that switching from semaglutide to tirzepatide produced an additional 4.2 kg mean weight loss over 40 weeks, even when semaglutide had been titrated to maximum dose

Recent evidence suggests their therapeutic potential in various diseases, though their efficacy and safety remain incompletely understood

In fact, liraglutide, the generic form of Saxenda now being produced by Teva, shares over 97% sequence homology with human-derived GLP-1

With the nausea, vomiting and pain gone, her appetite returned and she regained weight.

First, it suggests that the benefits require ongoing treatment rather than producing permanent changes
