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Basilea originally partnered with Johnson & Johnson to develop the molecule in 2005 but ran into a series of regulatory challenges

Introduction# Aleniglipron (GPCR0803, Structure Therapeutics) and orforglipron (Eli Lilly) are both oral non-peptide small molecule GLP-1 receptor agonists, representing the future of injection-free obesity treatment
Prolonged hemodialysis may be considered if clinically appropriate

If you ever experience severe stomach pain, persistent vomiting, or signs of an allergic reaction, stop the medication and contact a healthcare professional straight away
