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Ocular hypertension triggers the production of pro-inflammatory cytokines by immune cells, which in turn drives the transformation of neuroprotective astrocytes into a neurotoxic A1-reactive phenotype, ultimately leading to RGC degeneration [45]

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[DOI] [PubMed] [Google Scholar] [48].Evangelou K, Vasileiou PVS, Papaspyropoulos A, Hazapis O, Petty R, Demaria M, et al

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