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Though both the exposure and comparison cohorts were drawn from the same platform, which should not significantly impact the relative hazard rate ratios, results from the TriNetX platform need to be validated in other populations and platforms of EHRs

[1] [2] That said, people with diabetes in general have a higher baseline risk of developing urinary tract infections compared to the non-diabetic population

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Large-scale epidemiological studies have confirmed that metformin users have a significantly lower risk of developing various malignancies, including bladder, lung, prostate, pancreatic, head and neck, esophageal, liver, and colorectal cancers, compared to non-users [10]