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People with existing kidney issues may notice worsening symptoms while taking these medications

GLP-1 is important in diabetes management because it stimulates insulin production, inhibits glucagon release, and slows gastric emptying, helping control blood sugar levels

N Engl J Med 387(3):205216 Jastreboff AM, le Roux CW, Stefanski A, Aronne LJ, Halpern B, Wharton S, Wilding JPH, Perreault L, Zhang S, Battula R, Bunck MC, Ahmad NN, Jouravskaya I (2025) SURMOUNT-1 investigators

[DOI] [PMC free article] [PubMed] [Google Scholar] 146.Bliddal H, Bays H, Czernichow S, Uddn Hemmingsson J, Hjelmesth J, Hoffmann Morville T, et al

Clinical studies have found that high-fiber diets can improve blood sugar control and keep you feeling satisfied after eating by stimulating the release of GLP-1 on their own