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Evidence boundary No clinical trial has tested cagrilintide and retatrutide together

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These limitations highlight the need for prospective studies to confirm and expand upon these findings

Aad Withaar and his colleagues developed a mouse model that includes advanced age, female sex, in concert with co-morbidities: elevated blood pressure, obesity and type 2 diabetes mellitus and demonstrated that this model recapitulates the human cardiometabolic HFpEF phenotype

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