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Mazdutide Mazdutide (IBI362), co-developed by Innovent Biologics and Eli Lilly, is a long-acting synthetic peptide similar to mammalian oxyntomodulin (OXM) with a fatty acid side chain attached thereto
Diabetics with the greatest risk are the ones increasingly adopting GLP-1s
On the other hand, chronic GLP-1 activity in -cells increases its own secretion, feeding an autocrine loop that gets overstimulated with the use of exogenous synthetic GLP-1R agonists [(98)
Prentki M, Matschinsky FM, Madiraju SR
